The formulation and processing conditions employed in the manufacture of medicinal and biological products have a significant effect upon their safety, quality...

The formulation and processing conditions employed in the manufacture of medicinal and biological products have a significant effect upon their safety, quality and efficacy. Even apparently minor changes to the incoming materials and/or processing conditions can have a significant effect on content uniformity, stability, bioavailability, and other critical quality attributes which are not detectable by routine Quality Control testing. The Qualified Person (QP) must understand all aspects of pharmaceutical manufacture.

This module will focus on teaching theoretical basis and traditional and advanced experimental approaches in pharmacology. It will introduce quantitative...

This module will focus on teaching theoretical basis and traditional and advanced experimental approaches in pharmacology. It will introduce quantitative principles that underlie the study of the action of drugs through receptors. The molecular nature of receptors will be considered in detail and a critical and quantitative approach to the analysis and interpretation of pharmacological data will be developed. Further, application of modern cell biological and fluorescent techniques in receptor pharmacology will be considered. Finally, neurotransmitter release mechanisms, calcium homeostasis  and      secondary messenger cascades will be examined experimentally.

This module aims to provide extensive training in theoretical basis and traditional and advanced experimental approaches in pharmacology. The goal is to allow students to learn about topical areas of pharmacology and therapeutics from scientists who are leaders in their field and to critically appraise current literature. Specific aims are to develop a critical and quantitative approach to the analysis and interpretation of pharmacological data, written and verbal communication of science, reference retrieval and management and graphical processing.

Intellectual (thinking) skills: ability to disseminate complex data and concepts, critical thinking, problem solving, creativity.

Practical skills:(i) in-depth understanding and application of classical and contemporary pharmacological and therapeutic techniques; (ii) literature search-based data acquisition and analysis; (iii) manage and design a project, manage time efficiently, learn techniques and methodologies in current pharmacology/therapeutics research; (iv) presentation of ideas, concepts and original research in a clear and concise manner.