Aims:

This module provides an introduction to computer programming using two different programming styles, imperative and functional programming. Its primary...

One of the crucial developments of the period we term ‘the Renaissance’ or ‘early modern’ was the rise of a multitude of cultural forms...

One of the crucial developments of the period we term ‘the Renaissance’ or ‘early modern’ was the rise of a multitude of cultural forms in the vernacular, in contrast to the medieval Latinate world that had gone before. We will look at how these changes developed in different European countries from their origins in Italy to Spain, England and France. As well as charting these key shifts in cultural practice, we incorporate sessions that introduce crucial changes in material practice, focusing on print culture, communication networks, and visual, aural and material culture. These sessions are designed to complement and dialogue with other modules on the MA in Early Modern Studies that develop the necessary skills for carrying out original research for the dissertation and towards doctoral study, i.e. historical bibliography and the study of manuscript material. In addition to weekly seminar discussion, we will visit libraries, archives and sites of special interest (when possible) including the National Portrait Gallery, and these visits will include sessions on object-based learning.

The overall learning objective for this module is for you to gain knowledge and understanding of the transformation in diagnosis and management of cancer as a...

The overall learning objective for this module is for you to gain knowledge and understanding of the transformation in diagnosis and management of cancer as a result of the ability to predict, prevent and personalise treatment based upon knowledge of each individual patient. This module builds upon the knowledge contained in the Year 2 Cancer Biology and Therapeutics module. This module will consist of a mixture of lectures, interactive tutorials and self-directed learning.

The initial part of the module will focus on defining what is meant by precision cancer medicine and the experimental and diagnostic approaches used in the laboratory and clinic. This may include the role of transcriptomics, genomics, proteomics, epigenomics, metabolomics, molecular imaging or circulating biomarkers.

The focus will then turn to therapeutics. This will be in the form of specific case studies around the underlying biology and rational development of targeted small molecule, biological, cell based or radiotherapy treatments for solid tumours and haematological malignancies. These could include: Gleevec for the treatment of chronic myeloid leukaemia, Herceptin for the treatment of breast cancer, Rituximab for the treatment of lymphomas, or PARP inhibitors in ovarian cancer; the targeting of mutant B-raf in melanoma, epidermal growth factor receptor in lung cancer, or targeted radiotherapy of brain tumours; or the use of antibody drug conjugates, CAR T-cell therapy or Anti-PD-1/PD-L1 therapies.