Humanity continuously faces persistent, multifaceted and wicked problems, not least the unrelenting climate change and COVID-19 global health challenges, which expose societal vulnerabilities in pervasive and far-reaching proportions. In this backdrop, the relevance and complexity of development, technology, innovation and public policy discourses couldn’t have been more poignant.  Yet we all know that the relationship between technologies, innovations and development is a long and enduring one - a long-standing subject of many scholarly, policy and practice debates.  This Module provides students with an opportunity to learn the process by which scientific knowledge is generated and marshalled in both developing and developed countries, and how technologies and innovations are harnessed to promote broad-based development and address local, national and global challenges.  The Module critically examines the historical evolution and contemporary pathways of current innovation systems in developed and developing country contexts as a way to understand the range of technological development trajectories and options for low-and-middle-income countries in different parts of the world, including Asia, Latin America and Africa.  Anchored in innovation systems thinking, this Module explores the following themes: multiple narratives and conceptual underpinnings of innovation and development; emerging scientific and technological trends and their relevance for development; the role of innovation systems in sectoral, national and global development; public sector capabilities for governing science, technology and innovation in emerging economies; technological learning, catching-up and leapfrogging; path-dependency and lock-in in innovation and development; political economy, institutional and human capacity contexts for STI and development. The role of Sustainable Development Goals (SDGs) as a lever and galvanising framework for development will be explored closely throughout the Module. 