Module Description

Our ability to understand the intimate workings of mind, body and the maladies that affect them is limited by the techniques at our disposal and our ability to make use of them. This module will train students in canonical and contemporary methods in neuroscience, physiology and pharmacology, through a series of practical classes, workshops and extended lab visits that will allow students to observe cutting edge research occurring in the department of Neuroscience, Physiology and Pharmacology and partner institutes 

Indicative list of practicals: 

Fundamentals of Neuronal Electrophysiology: A Computer Simulation Practical. Students will use an in silico model of a neuron, to simulate the effects of varying different parameters on the underlying electrical activity of the neuron. The practical will be assessed through completion of a worksheet. This training is germane to the understanding of neuronal function and essential background for students wishing to undertake a PhD using electrophysiological techniques in the future. 

Parkinson's Practical. 
Students will analyse video data showing mouse locomotor behaviours and responses to drugs that impinge on monoaminergic function. The practical will be assessed through completion of a write-up/grant proposal. This training will help the students to appreciate the value of animal behavioural assays in the evaluation of mechanisms of neuroactive drug action. 

Neuroscience Methods: Laboratory visit 
Students will be divided into small groups and each group will be assigned to visit an active research laboratory in the department (or partner institution). During the visit a researcher will demonstrate experimental techniques associated with their current projects. This training will provide students with experience of cutting-edge techniques in neuroscience, physiology and pharmacology. The experience will inform aspirations towards postgraduate work in the form of MSc and PhD projects. The lab visit will be assessed through a group presentation. 

Indicative list of workshops: 

- Electrophysiological Techniques 

- Microsopy 

- Calcium Imaging 

- Behavioural Approaches 

- Critical Analysis 

- Molecular Techniques I 

- Molecular Techniques II 

- Opto and Chemo-Genetics 

- Experimental Design 

- Statistical Analysis 

A learning package will be provided a week before each workshop. Workshops will take place in person and will include an in-depth discussion of the relevant techniques. Learning will be assessed through technique focused student group presentations and an experimental design focused in-course assessment. 