Students will learn the key principles of formulating small molecule active ingredients. Mainstream techniques such as tableting and capsule manufacture will...

Formulation of Small Molecules (PHAY0033)

Students will learn the key principles of formulating small molecule active ingredients. Mainstream techniques such as tableting and capsule manufacture will be introduced, with further discussion of advanced modified release systems and how to assess drug release from a formulation. The focus will be on oral delivery, but with homage paid to other administration routes, particularly pulmonary, dermal, and ocular delivery.

 List of lectures:

  Introduction to formulation of small molecules
 
  Oral drug delivery
 
  Dry powder inhalers
 
  Rectal / vaginal drug delivery
 
  Topical / transdermal drug delivery
 
  Inhalation
 
  Oromucosal drug delivery
 
  Ocular drug delivery
 
  Nail drug delivery

MECHANICAL PROPERTIES|ELASTIC AND PLASTIC DEFORMATION|MICROSTRUCTURE|ATOMISTIC SIMULATION

Outline and Aims:

The aim of the course is to provide students with:


	Knowledge and understanding of the mechanical, electrical and optical properties of a...

Materials and Energy Materials (PHAS0055)

Outline and Aims:

The aim of the course is to provide students with:

Knowledge and understanding of the mechanical, electrical and optical properties of a variety of materials, including metals, ceramics, polymers, composites, and energy materials.
	Knowledge and understanding of the relationship between material properties and the microstructure, and how material properties can be obtained from atomistic simulation.
Teaching and Learning Methodology:

This course is delivered via weekly lectures supplemented by a series of workshops and additional discussion.

In addition to timetabled lecture hours, it is expected that students engage in self-study in order to master the material. This can take the form, for example, of practicing example questions and further reading in textbooks and online.

Indicative Topics:

Background [5]: Introduction to material science and nanomaterials: structure and bonding, defects, diffusion

Microstructure and mechanical properties of metal alloys [10]: Mechanical properties: elastic and plastic deformation, strengthening mechanisms Failure, fracture, fatigue and creep; Mechanical properties of nanostructured materials; Phase diagrams: binary isomorphous and eutectic systems, iron-carbon phase diagram: Microstructure in steels; Phase transformations; Alloys: light alloys, superalloys, nanostructured alloys

Non-metallic materials [5]: Ceramics: structure, properties, processing, glasses, carbon-based materials; Polymers, structure, properties, processing, thermoplasts, thermosets and elastomers, viscoelasticity; Composites

Materials for solar energy conversion and storage [5]: Materials for solar cells, photoelectrochemical cells, water splitting and CO2 reduction (i.e. artificial photosynthesis), batteries, supercapacitors

Atomistic modelling of materials [5]: Force fields, molecular dynamics and Monte Carlo, materials properties from simulation, simulation of carbon-based materials, charge transport in solar cells.