Bioprocess Synthesis and Process Mapping (BENG0033)

To provide the basic principles of bioprocess analysis and design. This will be achieved by first introducing students to the concept of whole bioprocess sequences and process flow sheets. Mass balance techniques for the key unit operations within the bioprocess sequence will then be taught.

Upon completion of the course, a student should be able to:

Learn the fundamental principles underpinning the main bioprocess unit operations.
	Understand the principles of mass and energy balancing and how this is used in process analysis.
	Familiarise with primary separation processes and conduct mass and energy balances on these.
	Learn different methods of product release by homogenisation, conduct an analysis of selective release options and consider the impact of product release on subsequent unit operations.
	Understand the principle of chromatographic beds and beads function, be able to interpret adsorption isotherms and modes of action and conduct a mass balance analysis of chromatography operations.
	Familiarise with formulation and product dose forms suitable for biological medicines and with the definition of drug substance and drug product.
	Apply design principles and define process specifications for different biopharmaceutical process examples

This is a 30 credit design module in the MArch Bio-Integrated Design in which students will be introduced to the programme’s experimental design culture...

Bio-Integrated Design: Preliminary Design (BARC0182)

This is a 30 credit design module in the MArch Bio-Integrated Design in which students will be introduced to the programme’s experimental design culture through a series of short projects.
Numerous seminars and workshops with invited experts in the field such as architecture, product design and material science, biology will underpin the students design explorations that will be done individually in the first weeks and in groups until the interim reviews. The projects are inherently design oriented, but they are also important to engage students with new research agendas in which they learn the basics of biological/ecological thinking, growth and lab protocols, speciation, bioreceptivity concepts, environmental and water dynamics, along with material considerations.