The aim of the module is to impart an understanding of what medicinal chemists consider when attempting to design new pharmaceuticals. The module will describe the principles involved in modern drug design and drug discovery, usually with reference to compounds in current clinical usage. Topics to be covered include: an introduction to the basis of drug design and development: molecular size, shape and charge in drug action, quantitative structure-activity relationships; antibacterial and antifungal chemotherapy; enzyme inhibitors as drugs and antiviral and anticancer chemotherapy.

MODULE AIMS

Understand how to relate chemical structure to biological activity.

Understand how to conduct a structure-activity analysis.

Appreciate the various approaches to drug discovery and to be able to exemplify them

TEACHING AND LEARNING METHODS

Lectures: The topics will be introduced through a blended delivery of asynchronous videos with online activities, and support hours. In addition, there will be contributions by speakers from the pharmaceutical industry. The material in these lectures will also be examinable; however, there will not be a separate question on the exam paper specifically for these lectures.

Self-study: In addition to timetabled hours it is expected that you engage in self-study in order to master the material. This can take the form of practicing example questions (additional questions available on Moodle and past exam questions) and further reading in textbooks and online.

The Report (30 credits) consists of an extended critical literature review on a music education topic, the development of a philosophical argument, or a piece...

The Report (30 credits) consists of an extended critical literature review on a music education topic, the development of a philosophical argument, or a piece of empirical research in a music education context thus evidencing knowledge and skills associated with qualitative or/and quantitative social and educational research approaches and their literature.