FRAGMENT BASED DRUG DESIGN|DRUG DESIGN|VIRTUAL SCREENING

This module will teach you two important concepts in drug discovery.  The first is Fragment-Based Drug Design and how it is applied in drug discovery projects....

This module will teach you two important concepts in drug discovery.  The first is Fragment-Based Drug Design and how it is applied in drug discovery projects. It has been regularly used during the past 15 years, and many new drugs have been discovered as a result.

The second is virtual screening or docking. This is a technique that uses computer power and advanced computational techniques to screen millions of potential drug molecules.

The unique tutorial and practical sections will equip you with good skills in using online databases and modern computational techniques:

Virtual screening / Docking and software
 Basic Python programming using RDKit
 Online chemical databases

GENETIC NEOPLASTIC  MOLECULAR MECHANISMS DISEASE|DRUG DISCOVERY

This module provides a comprehensive overview of the diverse genetic, cell and molecular mechanisms underlying human disease. Topics include Genetic diseases,...

This module provides a comprehensive overview of the diverse genetic, cell and molecular mechanisms underlying human disease. Topics include Genetic diseases, Neoplastic Disease (Cancer), Infection (bacterial and viral), Inflammatory disorders (diseases of the immune system), and Environmental and Nutritional diseases (often referred to as ‘Life-Style disorders’). Analysis of pharmaceutical industry perspectives on drug discovery for human diseases is also covered. The module will provide a thorough and in-depth understanding of the complex mechanisms underlying common and rare human diseases, and how unravelling mechanisms can lead to applied medical science, and the development of targeted treatments resulting in clinical solutions for diverse human conditions.

Aims:

Overall, the module represents an introduction to the topic of systemic risk and stress propagation in networked systems. The first part of the module...