SOIL CLASSIFICATION|STRESSES AND STRESS PATH|GROUNDWATER|SOIL TESTING|SETTLEMENT|STRENGTH

This module aims to provide knowledge and understanding of fundamental principles of soil mechanics and to teach how to use these principles in civil...

This module aims to provide knowledge and understanding of fundamental principles of soil mechanics and to teach how to use these principles in civil engineering practice.

Learning Outcomes

Describe and classify porous soils and calculate basic properties
	Understand the importance of water and apply the effective stress concept
	Analyse steady state water flow through soils
	Analyse one-dimensional long-term settlements in soils
	Understand the deformation behaviour of soils under various conditions
	Apply basic Mohr Circle and stress path concepts to describe the failure of soils
	Problem solving skills
	Laboratory skills
	Presenting information textually and graphically.
Reading List:

An Introduction to the Mechanics of Soils and Foundations / J.H. Atkinson. London: Spon Press.
	Soil mechanics: concepts and applications / William Powrie. London: Spon Press.

This module focuses on the mechanism of cancer generation and progression and on the most advanced treatments. Starting with a background integrating genetic,...

This module focuses on the mechanism of cancer generation and progression and on the most advanced treatments. Starting with a background integrating genetic, cellular and molecular aspects, it covers recent cancer research leading to a general conceptual framework for the development of this disease. The module also provides insights and illustrations from specific cancer types and concludes with a variety of established and emerging treatments. The overall aim of this module is to provide a strong background for careers related to basic cancer research, experimental medicine and drug discovery.

Indicative lecture list (based on 2021/22 syllabus)

Properties of transformed cells

Cell division and cell cycle

Cellular senescence and immortalisation

Oncogenic subversion and signal transduction

Tumour suppressor genes

Angiogenesis in cancer

Cancer metabolism

Cancer Stem Cells

The role of metastasis in cancer

Intra-tumour Heterogeneity, Tumour Evolution and Adaptation

Epithelial cancer: breast cancer

Leukaemia’s

Novel therapeutics

Targeted cancer therapy

Exploiting DNA damage response in cancer therapy

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