The module aims to teach students about the use of genomics knowledge for drug discovery and the current state of pharmacogenetic research with an emphasis on...

Genomics and Drug Development (GENE0008)

The module aims to teach students about the use of genomics knowledge for drug discovery and the current state of pharmacogenetic research with an emphasis on translating genetic research findings into clinical benefit.



The module consists of two parts. The first is a series of 2hr long lectures which cover the human genome, human phenome, disesase-ome, principles of drug discovery and pharmacogenetics. In the second part, students will each be allocated a disease or disease area and will be asked to prepare a presentation giving background about the disease, a review of the various medications being used to treat the disease, a review of the current evidence for genetic differences determining response to medication and risk of adverse drug responses and a proposal for future research activities. 



Indicative lecture topics (based on 2019/20 syllabus)



Introduction to Course
 The Human Genome I
 The Human Phenome and Disease-ome
 Molecular, target, and structural aspects of drug action
 Introduction to Pharmacokinetics
 Applications of drug-target data in translating genomic variation into drug discovery opportunities
 Developmental Pharmacology
 Interpretation of predictive tests
 Tumour Heterogeneity and Drug Resistance
 Using Pharmacogenetic tests to avoid Adverse Drug responses
 Incorporating pharmacogenetics tests in clinical trials

This module will introduce you to the politics and power dynamics in healthcare organisations. You will learn to identify, analyse and critique concepts and...

Healthcare Power and Politics (GBSH0028)

This module will introduce you to the politics and power dynamics in healthcare organisations. You will learn to identify, analyse and critique concepts and theories concerning power and politics especially in regard to their relationship to resource allocation within organisations.  The module will incorporate a range of tools and frameworks to inform your understanding of power dynamics particularly in a healthcare setting.  You will also have several opportunities to put your learning into action through case studies and simulation exercises.  The aim is to get you to identify power relationships as well as learn how to influence and shape these relationships.  The module will also look at key leadership skills such as change management, conflict resolution, stakeholder engagement and negotiations in the workplace for addressing power dynamics. 

 

You will learn that “being political” is key to succeeding in any organisation and you must embrace navigating politics.  Your leadership and management skills will be enhanced through better understanding and engagement with power and politics.  Given the focus on healthcare as the organisational context, the political terrain within your organisation as well as the wider health sector will be used for advancing your influencing skills.  We will focus on ensuring that you gain the required emotional intelligence to not only identify the “rules of the game”, but engage in a manner to shape and influence decisions.