Summary

This module will provide an introduction to key molecular contemporary techniques used in cardiovascular research. You will undertake practical work...

An Introduction to Molecular Laboratory Methods in Cardiovascular Research (CARD0005)

Summary

This module will provide an introduction to key molecular contemporary techniques used in cardiovascular research. You will undertake practical work covering fundamental laboratory skills (pipetting, aseptic techniques etc.) and more advanced genetic/molecular biology methods such as genetic screening, sequencing methods and molecular cloning. This will be complemented by lectures, computer exercises, extensive e-learning resources and tutorials on topics related to practical sessions.

Learning Outcomes and Objectives 

Students successfully completing this module should:

Have practised fundamental laboratory methods in a research laboratory, or if laboratory access is restricted, via online methods
 Have acquired a good theoretical understanding of the key laboratory techniques taught in this module
 Have experienced and be able to use key computer based bioinformatics tools related to molecular cardiovascular research
Who is this module for? 

This is an optional module for iBSc Cardiovascular Science students. It is open to UCL BSc students from an allied subject.  

Teaching and Learning Methods

Learning will be through practical sessions, lectures, computer exercises, e-learning (online resources, videos and simulations of molecular laboratory methods) in addition to tutorials.

Selected Reading List 

Human molecular genetics 4. Tom Strachan and Andrew Read. New York; Abingdon: Garland Science 4th ed. 2011

Edwards J, Bartlett JM. Mutation and polymorphism detection: a technical overview. Methods Mol Biol. 2003;226:287-94.

George AL Jr. Use of contemporary genetics in cardiovascular diagnosis. Circulation. 2014;130(22):1971-80.

Pearson H, Stirling D. Cloning and mutagenesis: a technical overview. Methods Mol Biol 2003;226:464-499.