The field of natural language processing (NLP) is one of the most useful application areas of Artificial Intelligence which is now integrated in various...

Deep Learning for Natural Language Processing  (ELEC0141)

The field of natural language processing (NLP) is one of the most useful application areas of Artificial Intelligence which is now integrated in various aspects of our daily lives from smart phones to search engines. In this module we will explore the fundamental concepts of NLP as well as its intersection with modern deep learning technologies. By mastering cutting-edge approaches, students will gain the skills to move from basics of NLP to implementing complex deep learning models for real-world applications such as dialogue systems, automatic summarisation and translation, and question answering. The course will offer lab sessions and assignments specifically targeted at putting some of the learned technologies in practical use by implementing and deploying them on voice-activated devices. The main implementation tool to be used will be the TensorFlow library in Python, and TensorFlow Lite to run models on hardware and smart devices (i.e., mobile phones or tablets).

STEM CELLS|CELL THERAPY|CLINICAL TRIALS|GENE THERAPY

Summary 



The aim of this module is to teach you the historic, current and future cell and gene therapy treatment strategies. It will introduce concepts in...

Clinical Applications of Cell and Gene Therapy (CHLD0032)

Summary 



The aim of this module is to teach you the historic, current and future cell and gene therapy treatment strategies. It will introduce concepts in clinical and basic research, clinical trials and methodology. In particular it will cover: Principles of stem cell transplantation, including bone marrow transplantation; rationale for treating particular diseases by cell and gene therapy; principles and practice of clinical trials of cell therapy (e.g. clinical trials for genetic blood disorders, clinical trials for muscle, liver, skin, lung and metabolic disorders); , including stem cell transplantation, immunotherapy and gene therapy ; discussion of regulation and monitoring required for such clinical studies.



Learning Objectives and Outcomes 



After taking this module, you should be able to:

Understand the process, principles and regulation of bringing cell and/or gene therapies from the bench to the bedside
 Have awareness of the current scope of cell and gene therapy in clinical practice
 Have a grounding in cell and gene therapy technologies sufficient to form a generalised plan for moving a novel laboratory finding to clinical practice
Who is this module for? 



This is a core module for the MSc Cell and Gene Therapy.



Teaching and Learning Methods 



This module will be delivered mostly as a series of lectures by ICH/UCL staff with some external experts. There will be the opportunity for you to attend additional ICH/UCL research seminars, journal clubs and lab meetings (though this is not compulsory).





Selected Reading List 



Sadelain, M., Rivière, I. & Riddell, S. Therapeutic T cell engineering. Nature 545, 423–431 (2017).

Booth et al., (2019) Gene therapy for primary immunodeficiency. Human Molecular Genetics 28: 15-23

Cavazzana M et al., (2019) Gene therapy targeting haematopoietic stem cells for inherited diseases: progress and challenges. Nature reviews Drug Discovery 18:447-462