This module will look at the potential harmful effects of compounds, and how these can be minimized through toxicology risk assessment. It will cover how xenobiotics are toxified and detoxified through Phase I and Phase II metabolic processes; the molecular mechanisms through which toxins and toxicants produce their deadly effects; immunotoxicology; environmental toxicology; neurotoxicology; and how the toxic effects of compounds are predicted and measured. 

After taking this module, you should have a broad understanding of a variety of toxicological disciplines; from basic concepts to molecular mechanisms underlying specific examples of target-organ toxicities. You will learn about the toxicity of specific compounds to humans and the environment and gain insight into the process of nonclinical toxicity testing in drug development. 

The module is an option for iBSc/BSc/MSci Pharmacology and Physiology students. It can be taken as an elective by affiliate students, Biomedical and Natural Scientists, and Medicinal Chemists. Other students may be able to take the module but should contact the organiser for more information. Some background in Pharmacology is required. 

Indicative lecture list (based on 2021/22) 


	Introductory toxicology 
	
	
	Drug metabolism (two lectures) 
	
	
	Cheminformatics and predictive toxicology 
	
	
	Regulatory toxicology 
	
	
	Biomarkers of toxicity 
	

	Immunotoxicology 
	
	
	Toxins affecting neurotransmission 
	
	
	Neuropsychological aspects of toxin poisoning 
	
	
	Anticholinesterase toxicology 
	
	
	Toxicology of nicotine/smoking 
	

	Environmental toxicology 
	
	
	Case studies on neurotoxicity, pulmonary toxicity, hepatotoxicity and reproductive toxicity 
	
Plus one computer-based practical class on predictive toxicology. 

The operations and technology management element of this module focuses on operations and management of technology in a wide variety of industries. Operations...

The operations and technology management element of this module focuses on operations and management of technology in a wide variety of industries. Operations management is the design and management of the processes that transform inputs into finished goods or services. Operations is one of the primary functions of a firm, similar to Finance or Marketing. The operations and technology management element provides a foundation for understanding the operations of a firm by exploring a simple question: How do companies actually do things?

Operations management is also a key competence for consulting companies that are called to analyse and streamline the processes of their clients. Technology is often intertwined with the operations of a firm, so students will also see the interplay between technology and operations, and together how they can provide a critical competitive advantage. The operations and technology element focuses on operations in a wide variety of industries including manufacturing, technology, healthcare, hospitality, retailing, transportation, among others.

Operations Analytics focuses on quantitative frameworks that make use of data, statistics, and mathematics to guide managers to better decisions and ways to improve their organisation's operations and supply chains.